Abstract Background The atopic syndrome consists of heterogeneous manifestations, in which igora vibrance 6-68 multiple associated genetic loci have recently been identified.It is hypothesized that immune dysregulation plays a role in the pathogenesis.In primary immunodeficiency diseases (PIDs), which are often monogenic immunodysregulation disorde
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It has been shown that gene body DNA methylation is associated with gene expression.However, whether and how deviation of gene body DNA methylation between duplicate genes can influence their divergence remains largely unexplored.Here, we aim to elucidate the potential role of gene body DNA methylation in the fate of duplicate genes.We identified p